Serenex, Inc., an integrated oncology-focused tablets appreciation and advancement business, announced today the beginning of a point 2 clinical experimentation of its face article of trade, SNX-1012. The drawn-out will be tested in patients beside guaranteed dense tumors who be excess with chemotherapy and refine oral mucositis. The chalet will equate multiple dose of SNX-1012 resistant a placebo peacefulness and be looked-for to be completed in hasty 2007.
"A considerable section of refuge information right now be real all for this compound. Therefore, demonstrating efficacy and identify the optimal dose during this phase 2 clinical trial will be an even more in extra opinionated rung toward the development of SNX-1012," said Dr. Richard Kent, chief executive officer at Serenex. "Treatment option for patients victims from chemotherapy and radiation-induced oral mucositis are desperately controlled, and fundamentally, within is currently no powerful conduct for the thereabouts 400,000 solid tumor patients in the United States suffering from oral mucositis," Dr. Kent added.
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SNX-1012 target multiple inflammatory and other push button pathway ensnared in the pathophysiology of oral mucositis. The product is administered in place of a topical, transmucosal agent in the gel of an oral tidy up that interfere with abundant of the birth targets elemental for mucositis development. Four phase 1 trial have been proudly completed, together with a phase 1b study at the Fred Hutchinson Cancer Center in Seattle, which live entertainment authoritative indication of pharmacological buzz and an unparalleled safety profile.
About Serenex Serenex is an integrated oncology-focused drug discovery and development company. The company's pursuit is to present the live of cancer patients by mushrooming proprietary remedial and supportive safekeeping products. Serenex's lead program, SNX-1012, a product for chemotherapy and radiation-induced oral mucositis, is programmed to completed phase 2 clinical trials in early 2007.
MultiStem cell be proprietary fully developed banister cells derived from bone marrow, which have the demonstrated ability to outline a widespread catalogue of cell kind. MultiStem may execute through several mechanisms, but a primary contraption appear to be the yield of multiple invigorating molecules produced in comeback to inflammation and tissue trash. Athersys believes that MultiStem act in place of a multi-factor tablets transference system, and represent a fantastically rare "off-the-shelf" stem cell product based on its professed ability to be beforehand individual lacking tissue also brought-up as or immunosuppression and its dimensions for extensive mass production. Based on research conduct by Athersys and its big business partner, Lonza, the company believes that things from a free qualified benefactor may be used to assemble hundreds of thousand or even millions of clinical dose of MultiStem.
Serenex, Inc./
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